Table 1 Demographic and clinical data in relation to neurophysiological variants at admission.
Clinical findings at onset | AIDP | Primary axonal including inexcitable forms | p value* |
|---|---|---|---|
(N = 31) | (N = 26) | ||
Demographic data | |||
Age: mean SD (range of age years) | 36.81 ± 18.31 | 34.24 ± 16.13 | 0.58 |
Sex: Male/Female Number (%) | 18/13(58.1/41.9%) | 14/12(53.8/46.2%) | 0.74 |
Residency: Urban/Rural Number (%) | 14/17(45.2/54.8%) | 8/18(30.8/69.2%) | 0.27 |
Duration of each event | |||
Days between antecedent event and onset of GBS: Mean ± SD | 8.26 ± 7.57 | 7.58 ± 7 | 0.72 |
Duration of antecedent event: Mean ± SD | 1.84 ± 1.61 | 1.85 ± 1.51 | 0.98 |
Days between onset of weakness and admission: Mean ± SD | 8.1 ± 5.04 | 5.35 ± 3.63 | 0.02 |
Number of cases with antecedent events = 39 (68.4%) | 17(54.8%) | 22(84.6%) | 0.016 |
Upper RT infection ± fever: Number (%) | 14(82.35%) | 12(54.54%) | 0.94 |
GIT infection: Diarrhea ± vomiting: Number (%) | 3(17.6%) | 10(45.45%) | 0.01 |
Days between onset and admission | |||
> 7 days | 14(45.2%) | 7(26.9%) | 0.15 |
4–7 days | 7(22.6%) | 4(15.3%) | |
≤ 3 days | 10(32.3%) | 15(57.6%) | |
Days between onset and electrophysiology study | |||
> 10–15 days | 15(48.4%) | 6(23.1%) | 0.14 |
5–10 days | 15(48.4%) | 19(73.1%) | |
≤ 4 days | 1(3.2%) | 1(3.8%) | |
Cranial nerves affection | |||
Presence | 18(58.1%) | 19(73.07%) | 0.23 |
Absence | 13(41.9%) | 7(26.9%) | |
Papilledema and blurred vision | |||
Present | 5(16.1%) | 8(30.7%) | 0.19 |
Absent | 26(83.9%) | 18(69.2%) | |
Neck muscle | |||
Affected | 9(29%) | 17(65.38%) | < 0.006 |
Not affected | 22(71%) | 9(34.6%) | |
Sensory affection | |||
Hypoesthesia | 29(93.5%) | 13(50%) | < 0.0001 |
Intact sensation | 2(6.5%) | 13(50%) | |
Cough reflex | |||
Impaired cough reflex | 12(38.7%) | 18(69.2%) | 0.022 |
Preserved | 19(61.3%) | 8(30.7%) | |
MRC sum score | |||
At onset Mean ± SD | 27.16 ± 13.96 | 15.15 ± 11.45 | 0.001 |
At nadir Mean ± SD | 31.16 ± 13.93 | 18.23 ± 13.43 | 0.001 |
EGRIS at onset | |||
Low risk | 11(35.5%) | 0 | 0.001 |
Intermediate risk | 7(22.6%) | 7(26.9%) | |
High risk | 13(41.9%) | 19(73.07%) | |
Mechanical ventilation | |||
Mechanical ventilated | 0 | 4(15.3%) | 0.024 |
Not ventilated | 31(100%) | 22(84.6%) | |
Autonomic affection (dysautonomia) | |||
Present | 7(22.6%) | 10(38.4%) | 0.192 |
Absence | 24(77.4%) | 16(61.5%) | |
Treatment | |||
Plasma exchange | 24(77.4%) | 22(84.6%) | 0.49 |
IVIG | 7(22.6%) | 4(15.3%) | |