Table 1 Description of the six metabolic risk factors with available genetic data from GWAS.
From: Mendelian randomization analysis revealed potential metabolic causal factors for breast cancer
Risk factor | Number of SNPs | Study reference | Sample size | Population | Year |
|---|---|---|---|---|---|
BMI | 941 | Yengo et al.38 | 681,275 | European | 2018 |
BMI female | 12 | Randall et al.39 | 67,957 | European | 2013 |
Height | 697 | Wood et al.40 | 253,288 | European | 2014 |
Height female | 323 | Randall et al.39 | 67,957 | European | 2013 |
T2D | 139 | Xue et al.41 | 655,666 | European | 2018 |
T2D female | 14 | Morris et al.42 | 149,821 | European | 2012 |
HDL | 534 | Richardson et al.43 | 403,943 | European | 2020 |
HDL female | 323 | Kanoni et al.44 | 565,724 | European | 2022 |
LDL | 220 | Richardson et al. 43 | 440,546 | European | 2020 |
LDL female | 281 | Kanoni et al.44 | 558,498 | European | 2022 |
TG | 313 | Richardson et al. 43 | 441,016 | European | 2020 |
TG female | 296 | Kanoni et al.44 | 558,498 | European | 2022 |
