Table 2 Correlations between biomarkers, clinical activity, and blood markers.

From: Combined serum albumin, fecal immunochemical test, and leucine-rich alpha-2 glycoprotein levels for predicting prognosis in remitting patients with ulcerative colitis

 

FIT

CRP

ESR

Alb

Plt

Hb

LRG (n = 194) 95% CI

0.1932 (0.0204–0.3549)

0.7433 (0.6729–0.8004)

0.5682 (0.4421–0.6722)

− 0.5372 (− 0.6308 to − 0.4282)

0.3687 (0.2403–0.4844)

− 0.3850 (− 0.4988 to − 0.2581)

p value

0.0289

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

FIT (n = 128) 95% CI

 

0.2395 (0.06886–0.3966)

0.1152 (− 0.08839–0.3096)

− 0.2103 (− 0.3709 to − 0.0374)

0.007192 (− 0.1666–0.1805)

− 0.01456 (− 0.1876–0.1594)

p value

 

0.0065

0.2663

0.0177

0.9358

0.8704

CRP (n = 194) 95% CI

  

0.4621 (0.3185–0.5849)

− 0.3035 (− 0.4267 to − 0.1691)

0.2362 (0.09858–0.3649)

− 0.1448 (− 0.2799 to − 0.00396)

p value

  

 < 0.0001

 < 0.0001

0.0009

0.0440

ESR (n = 136) 95% CI

   

− 0.4703 (− 0.5926 to − 0.3268)

0.2550 (0.09051–0.4059)

− 0.5262 (− 0.6380 to − 0.3926)

p value

   

 < 0.0001

0.0027

 < 0.0001

Alb (n = 192) 95% CI

    

− 0.4703 (− 0.5926 to − 0.3268)

0.2550 (0.09051–0.4059)

p value

    

 < 0.0001

0.0027

Plt (n = 194) 95% CI

     

− 0.2934 (− 0.4171 to − 0.1592)

p value

     

 < 0.001

  1. 5-ASA 5-aminosalicylic acid, LRG leucine-rich alpha-2-glycoprotein, FIT fecal immunochemical test, CRP C-reactive protein, ESR erythrocyte sedimentation rate, Alb albumin, Plat platelet count, Hb hemoglobin, CI confidence interval.
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