Table 3 Univariate and multivariate analyses for predicting clinical relapse in remitting patients.

From: Combined serum albumin, fecal immunochemical test, and leucine-rich alpha-2 glycoprotein levels for predicting prognosis in remitting patients with ulcerative colitis

 

Non-relapse (n = 81)

Relapse (n = 24)

Univariate analysis

Multivariate analysis

p-value

HR

95% CI

p-value

Male/female

43/38

10/14

0.3908

   

Age median [range]

40 [17–88]

48.5 [22–81]

0.2571

   

Duration of disease [years] median [range]

7 [0.08–29]

8 [0.17–24]

0.7711

   

LRG median [range]

10.5 [5–28.1]

11.7 [7.3–23.9]

0.3106

   

Hemoglobin [g/dL] median [range]

14.1 [10.1–18.2]

13.4 [10.9–16.6]

0.4408

   

CRP [mg/dL] median [range]

0.041 [0.008–0.868]

0.0355 [0.008–0.587]

0.3581

   

ESR [mm/h] median [range] n = 74

5.2 [0.2–36.8] (n = 63)

6.3 [5.3–16.7] (n = 11)

0.8610

   

Alb [g/dL] median [range] n = 104

4.5 [3.8–5.1] (n = 80)

4.3 [3.2–5.1] (n = 24)

0.0108

0.1868

0.0435–0.7705

0.0220

Platelet [× 104/μL] median [range]

23.9 [12.4–51.1]

22.75 [15.2–37.1]

0.7278

   

FIT median [range]

20 [20–24224]

48.5 [20–39596]

0.0161

1.0001

1.0000–1.0001

0.001

pMayo

0 [0–2]

0 [0–1]

    

 1/0

  

0.0315

   

 2/1

  

0.9989

   
  1. LRG leucine-rich alpha-2-glycoprotein, CRP C-reactive protein, ESR erythrocyte sedimentation rate, Alb albumin, FIT fecal immunochemical test, pMayo score partial Mayo score, HR hazard ratio, CI confidence interval.
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