Figure 1 | Scientific Reports

Figure 1

From: Integrative blood-based characterization of oxidative mitochondrial DNA damage variants implicates Mexican American’s metabolic risk for developing Alzheimer’s disease

Figure 1

ccf-mtDNA 8oxoG variant count is significantly elevated in the Mexican American population. (a) Log transformed ccf-mtDNA 8oxoG variant count grouped by population using an unpaired, two-tailed t-test (n = 122, t-statistic = 4.666, df = 120, P ≤ 0.0001). Error bars represent standard error of the mean. (b) Violin plot demonstrating distribution of 8oxoG variant count in MAs and NHWs (n = 122) with effect size and confidence interval plotted on right y-axis. Dashed lines indicate the mean and dotted lines represent the 1st and 3rd quartile. The triangle represents the difference of the means.

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