Figure 2

Estimation of individual pupil dilation response function (IRF, exemplified here for BG). The initial peak of the time derivative of the low-pass filtered mean pupil response to rapid darkening of continuous illuminance (black), which induces dilation, was approximated with a gamma probability distribution function (red). Data was zeroed after the initial pupil response of interest (trough after maximum peak inside 1.5Ā s) before function approximation to suppress noise. Pupil constriction, i.e., response to brightening, was not modeled, as LC activity mainly relates to dilation.