Figure 3

Representative HPLC chromatograms of chlorfenapyr metabolism by P450s. The overlaid chromatograms represent the results of 2 h incubations of 100 μl reactions containing a final concentration of 0.05 μM P450, 0.4 μM b5 and 10 μM compound in the presence (black) and absence (blue) of NADPH. Chlorfenapyr (C) and tralopyril (T) peaks are arrowed.