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Figure 1

From: Caffeine exacerbates seizure-induced death via postictal hypoxia

Figure 1

Acute experimental timeline. Male C57BL/6J mice on P50 underwent brain implantation surgery and diaphragmatic surgery (Day 0). Mice recovered for one week before beginning terminal experiment (Day 7). Mice were injected with either caffeine, theophylline, N6-Cyclopentyladenosine (N6) or CGS- 21,680, 30 min prior to infusion of kainic acid. Physiological parameters including heart rate, respiratory rate, brain partial pressure of oxygen and local field potential were recorded until death.

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