Figure 2

Serum metabolome profile for sex comparison relative to females. (A) ESI− OPLSDA scores plot and VIP scores plot, (B) ESI+ OPLSDA scores plot and VIP scores plot, (C) ESI− volcano plot of differentially expressed metabolites, (D) ESI+ volcano plot of differentially expressed metabolites and (E) enriched metabolite pathways and (F) enriched lipid pathways. *Thirteen clinically healthy animals were included in this comparison (six EBR (1.5) and seven SBR (3.4)).