Figure 3

Serum metabolome profile for health phenotype comparison (healthy vs. inflammatory) relative to inflammatory phenotype. (A) ESI− OPLSDA scores plot and VIP scores plot, (B) ESI+ OPLSDA scores plot and VIP scores plot, (C) ESI− volcano plot of differentially expressed metabolites, (D) ESI+ volcano plot of differentially expressed metabolites and (E) enriched metabolite pathways and (F) enriched lipid pathways. *Thirteen clinically healthy animals (six EBR (1.5) and seven SBR (3.4)) were compared with fourteen animals with inflammatory phenotypes (six EBR (5.1) and eight SBR (5.3)).