Table 1 Differentially expressed metabolites by subspecies (eastern vs. southern). Fold change values are relative to eastern black rhinoceros subspecies.

From: Metabolomic profiling implicates mitochondrial and immune dysfunction in disease syndromes of the critically endangered black rhinoceros (Diceros bicornis)

 

t. stat

p value

FC

Source ESI−

Taurodeoxycholic acid•

5.6855

1.21E−06

2.52131958

Tetradecanedioic acid•

7.0819

1.26E−08

2.45810676

12-Ketodeoxycholic acid•

4.4349

6.76E−05

2.18009379

Pentadecanoic acid•

3.5855

0.00088697

2.13582382

Indolelactic acid

5.5838

1.69E−06

2.02595388

Docosapentaenoic acid (22n-3)•

3.7582

0.0005339

1.96740629

Xanthine

3.4112

0.0014654

1.53526241

Uric acid

3.5014

0.0011315

1.53262735

4-Pyridoxolactone

− 3.621

0.00079968

0.47959939

Dihydrouracil

− 7.6175

2.25E−09

0.42519574

Ascorbic acid 2-sulfate

− 4.2768

0.00011058

0.2872719

Palmitoyl glucuronide•

− 6.9899

1.70E−08

0.23807027

Thromboxane B2•

− 4.056

0.00021803

0.22906063

Ergothioneine

− 4.406

7.40E−05

0.20150888

Source ESI+

Progesterone*•

2.2134

0.032494

6.47124629

Homovanillic acid sulfate

3.0715

0.0037737

4.39691326

Allopregnanolone•

2.4143

0.020312

3.13438286

18-Hydroxyeicosapentaenoic acid

2.5804

0.013547

3.03788485

Aspartylphenylalanine

6.6006

6.06E−08

2.87004594

Porphobilinogen

4.2751

0.00011119

2.40478626

Retinoic acid•

2.08

0.043814

2.32514366

Glycerol

3.8697

0.0003829

1.76333235

Orotic acid

2.172

0.035689

1.71008204

2-Methyleneglutaronitrile

2.7814

0.0081408

1.61873648

Oxazine

2.23

0.031281

1.55195428

Ferulic acid

2.0482

0.046976

1.54191347

4-Nitroaniline

2.6325

0.011895

1.51281985

2-Ketobutyric acid

− 4.5491

4.72E−05

0.49954186

Deferiprone

− 5.6743

1.26E−06

0.48999963

Alanine

− 3.8595

0.00039486

0.4894637

Valine

− 5.7294

1.05E−06

0.4890865

2,3-Diaminosalicylic acid

− 5.1713

6.45E−06

0.48388992

Citraconic anhydride

− 5.1704

6.47E−06

0.48066615

Pimelic acid•

− 4.4788

5.89E−05

0.45459926

Pentanamide•

− 2.6177

0.012345

0.43866384

Polylysine

− 5.3375

3.77E−06

0.39933318

Aminoadipic acid•

− 3.1819

0.0027889

0.39649309

Methylthiouracil

− 4.6962

2.96E−05

0.30091508

15-HETE•

− 2.1102

0.040991

0.254377

6-Hydroxyhexanoic acid

− 5.6445

1.38E−06

0.24319717

  1. •Indicates lipids.
  2. *Progesterone is likely not differentially expressed by subspecies. Thirteen healthy animals were included in this comparison: seven SBR and six EBR. Five out of six EBR were females, which presumably drove the differential expression of progesterone in this comparison.
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