Table 1 Perioperative and intraoperative parameters of the two study cohorts after the stage one lung wedge resection. Continuous variables were expressed in mean \(\pm\) standard deviation. For each clinical characteristics shown in the above table, no significant difference was found among the control group and treatment group at a 5% significance level. It showed covariate balance between control and treatment groups.

From: Non-steroidal anti-inflammatory drugs reduce pleural adhesion in human: evidence from redo surgery

Clinical characteristic

Treatment, with NSAIDa (n = 27)

Control, without NSAID (n = 17)

p-Value (2-sided test)

Age

61.7 ± 6.8

62.1 ± 7.5

0.88

Smoker

6 (22.2%)

7 (41.2%)

0.32

Diabetic

5 (18.5%)

5 (29.4%)

0.64

Hypertension

8 (29.6%)

7 (41.2%)

0.65

Asthma

0 (0%)

1 (5.9%)

0.39

History of Malignancy

9 (33.3%)

10 (58.8%)

0.18

History of Oncological therapy

5 (18.5%)

5 (29.4%)

0.40

Forced expiratory volume in one second (% predicted)

96.9 ± 14.9

87 ± 19.9

0.07

Diffusing capacity for carbon monoxide (% predicted)

99.2 ± 15.9

89.7 ± 20

0.09

Upper lobe resection

14 (51.9%)

8 (47.1%)

1.00

Uniportal VATSb

21 (77.8%)

14 (82.4%)

1.00

Right-side operation

21 (77.8%)

10 (58.8%)

0.32

Visceral pleural sealants

7 (25.9%)

3 (17.6%)

0.72

Smaller chest drain size (Fr 24)

21 (77.8%)

14 (82.4%)

1.00

Chest drain duration (days)

4.1 ± 2.5

4.6 ± 4.1

0.63

Length of stay (days)

5.8 ± 2.9

6.4 ± 3.2

0.55

Waiting time for redo operation (days)

104.8 ± 85.8

106 ± 73.9

0.96

  1. aNSAID: Non-steroidal anti-inflammatory drugs.
  2. bVATS: Video-assisted thoracic surgery.