Figure 2 | Scientific Reports

Figure 2

From: Modulation of colonic immunometabolic responses during Clostridioides difficile infection ameliorates disease severity and inflammation

Figure 2

Host gene expression responses to CDI enrich metabolic processes with a distinctive peak of inflammation versus recovery phase patterns. RNA-seq data from each given day of the 10-day dataset (day 0, 3, 4, 5, 8 and 10) from colonic C. difficile-infected and uninfected samples was normalized to uninfected day 0 and displayed as fold change. Each row was normalized such that the greatest log change was mapped to either 1 or -1 depending on the sign of the change. RNA-seq data was filtered to only include the genes associated with each KEGG pathway. Heat map of Hierarchically clustered genes associated with TCA cycle (A), the Oxidative phosphorylation (B), and glycolysis/gluconeogenesis (C) are displayed.

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