Table 1 Hormone levels of the patient with Carney complex.
From: Whole genome sequencing resolves 10 years diagnostic odyssey in familiar myxoma
Hormone | Value at age of 41 years | Values after 18 months of metformin treatment | Reference range |
|---|---|---|---|
TSH (mU/L) | 1.240 | 0.757 | 0.35 0–4.940 |
Midnight salivary cortisol (nmol/L) | 3.220 | ND | < 11.900 |
Urinary free cortisol (nmol/24 h) | 279.8 and 332.0 | ND | 100.0–379.0 |
ACTH (pg/mL) | 23 | 30 | 5–60 |
Serum cortisol (nmol/L) 08.00 am | 447.30 | 389.3 | 220–690 |
Serum cortisol (nmol/L) 24.00 pm | 304.30 | ND | < 136 |
Serum cortisol (nmol/L) following administration of | |||
1 mg dexamethasone | 65.450 | 65.180 | < 50 |
8 mg dexamethasone | 54.910 | ND | < 50 |
DHEA-S (umol/L) | 4.16 | ND | 1.65–11.00 |
Serum prolactin (ng/mL) | 11.08 | 7.95 | 1.39–24.20 |
IGF-1 (ng/mL) | 85.4 | 179.5 | 50.0–175.0 |
Serum ß-crosslaps (pg/mL) | 333 | 226 | 100–573 |
Serum osteocalcin (ng/mL) | 12.30 | 12.97 | 12.00–41.00 |
HOMA_insulin (uU/mL) | 24.72 | 4.79 | 2.60–24.90 |
HOMA_glucose (mmol/L) | 4.77 | 4.50 | 3.00–5.50 |
HOMA_index | 5.24 | 0.96 | 0.00–4.40 |
Oral glucose load, serum glucose 0 min (mmol/L) | 5.4 | 4.9 | |
Oral glucose load, serum glucose 120 min (mmol/L) | 7.2 | 5.4 | |
