Figure 11
From: New drug discovery of cardiac anti-arrhythmic drugs: insights in animal models
Scope of the review. Although arrhythmogenic properties of hiPSC-CMs are very relevant in all 3 principal application fields (basic research, drug screening, and regenerative therapy), we focus on the first one and on the second one to a lesser extent. Also, we link the hiPSC-based findings to the human/patient context whenever possible. (Paci, Michelangelo; Penttinen, Kirsi; Pekkanen-Mattila, Mari; Koivumäki, Jussi T. Arrhythmia Mechanisms in Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes. Journal of Cardiovascular Pharmacology77(3):300–316, March 2021. https://doi.org/10.1097/FJC.0000000000000972).
