Table 2 Across all time points, there is only one subcluster (cluster 7) that has significantly increased S1R expression in the SNI condition versus the Sham condition.

From: Sigma-1 receptor expression in a subpopulation of lumbar spinal cord microglia in response to peripheral nerve injury

Cluster

p-val (pooled)

p-val (3 days)

p-val (14 days)

p-val (5 months)

0

0.7211

0.9781

0.5108

0.07082

1

0.5203

0.9785

0.3721

0.1951

2

0.9048

0.9808

0.3034

0.8202

3

0.5819

0.3615

0.3527

0.9073

4

0.2918

0.6196

0.3174

0.2572

5

0.8458

0.8712

0.5612

0.4412

6

0.1699

0.1705

0.8881

0.266

7

0.003705

0.9176

0.01377

0.006416

8

0.6076

0.6627

0.7881

0.1087

9

0.6606

0.9503

0.5787

0.3409

10

0.2449

0.4477

0.2951

0.2061

11

0.2879

0.01223

0.9132

N/A

  1. Cluster 7 does not have significantly increased expression of S1R at the 3-day timepoint but does at both 14 days and 5 months. At the acute injury time timepoint of 3-days, cluster 11 has significantly increased expression of S1R in the SNI group but does not at 14-days or 5-months.
Back to article page