Table 3 Performance of clinical assessment to predict the need for 2nd TURB in the total cohort.

From: Xpert bladder cancer monitor to predict the need for a second TURB (MoniTURB trial)

Group

n

TP

FP

TN

FN

Sensitivity

Specificity

HG

LG

PPV

NPV

(a) Clinical assessment by treating physician’s discretion

 

 Control cystoscopy

57

0

0

55

2

0/2 (0%)

55/55 (100%)

 

0/2 (0%)

 

55/57 (96.5%)

 2nd TURB

114

34

80

0

0

34/34 (100%)

0/80 (0%)

28/28 (100%)

6/6 (100%)

34/114 (29.8%)

 

 Total

171

34

80

55

2

34/36 (94.4%)

55/135 (40.7%)

28/28 (100%)

6/8 (75%)

34/114 (29.8%)

55/57 (96.5%)

(b) Clinical assessment in pTa tumors by physician’s discretion

 

 Control cystoscopy

55

0

0

53

2

0/2 (0%)

53/53 (100%)

 

0/2 (100%)

 

53/55 (96.4%)

 2nd TURB

60

15

45

0

0

15/15 (97.1%)

0/45 (0%)

11/11 (100%)

4/4 (66.7%)

15/60 (25%)

 

 Total

115

15

45

53

2

15/17 (88.2%)

53/98 (54.1%)

11/11 (100%)

4/6 (66.7%)

15/60 (25%)

53/55

(96.4%)

  1. TP, true positive; FP, false positive; TN, true negative; FN, false negative; HG, sensitivity for high-grade; LG, sensitivity for low-grade; PPV, positive predictive value; NPV, negative predictive value.