Figure 5 | Scientific Reports

Figure 5

From: LINC01343 targets miR-526b-5p to facilitate the development of hepatocellular carcinoma by upregulating ROBO1

Figure 5

ROBO1 was a target of miR-526b-5p. (A) The binding sites between miR-526b-5p and ROBO1 were predicted by TargetScan. (B) The relationship between miR-526b-5p and ROBO1 was confirmed by dual-luciferase reporter assay in Hep3B and Huh-7 cells (n = 3). *P < 0.05 and **P < 0.001 versus wt group. (C) qRT-PCR analysis of ROBO1 expression in 40 pairs of HCC tumor tissues and the adjacent normal tissues. (D). qRT-PCR analysis of ROBO1 expressions in the HCC cells (Hep3B and Huh-7) and normal THLE2 cells (n = 3). **P < 0.001 versus THLE2 cells group. (E) Linear regression analysis of the association between LINC01343 and miR-526b-5p expressions in HCC tissues.

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