Figure 2
From: Carriers of HLA-DRB1*04:05 have a better clinical response to abatacept in rheumatoid arthritis
The HLA-DRB1*04:05 allele is directly linked to abatacept treatment response. A mediation analysis of the relationships between the HLA-DRB1*04:05 allele carriage, anti-CCP antibody titer, and the SDAI improvement rate 3 months after ABT treatment (n = 37). Solid lines represent significant associations, while the dashed line indicates a non-significant association.
