Table 2 HLA-DRB1 allele frequencies.
From: Carriers of HLA-DRB1*04:05 have a better clinical response to abatacept in rheumatoid arthritis
HLA alleles | Abatacept (n = 37) | Tocilizumab (n = 28) | TNF inhibitor (n = 41) | p‡ |
|---|---|---|---|---|
Total | 74 (100) | 56 (100) | 82 (100) | |
DRB1*01:01 # | 5 (6.8) | 3 (5.4) | 7 (8.5) | 0.77 |
DRB1*04:05 # | 17 (23) | 9 (16.1) | 20 (24.4) | 0.48 |
DRB1*04:06 | 2 (2.7) | 5 (8.9) | 3 (3.7) | 0.21 |
DRB1*04:10 # | 3 (4.1) | 2 (3.6) | 4 (4.9) | 0.93 |
DRB1*08:03 | 5 (6.8) | 4 (7.1) | 6 (7.3) | 0.99 |
DRB1*09:01 | 10 (13.5) | 10 (17.9) | 15 (18.3) | 0.69 |
DRB1*12:01 | 3 (4.1) | 2 (3.6) | 2 (2.4) | 0.85 |
DRB1*13:02 | 3 (4.1) | 1 (1.8) | 4 (4.9) | 0.64 |
DRB1*15:01 | 6 (8.1) | 0 (0) | 3 (3.7) | 0.072 |
DRB1*15:02 | 3 (4.1) | 7 (12.5) | 9 (11) | 0.18 |
Other DRB1 alleles | 17 (23.0) | 13 (23.2) | 9 (11.0) | 0.086 |
