Table 3 Results of analysis of variance models per brain region of interest of the differences in fiber density between COVID-19 patients (n = 18) and healthy controls (n = 17).

From: A cross-sectional case–control study on the structural connectome in recovered hospitalized COVID-19 patients

Brain region

Estimate (SE)

Adjusted R-squared

Significance level

Effect size [95% CI] (Hedges’ s g)

Corpus callosum

 Motor segment

Intercept

0.730 (0.012)

0.153

 < 0.001

0.884 [0.180–1.589]

Group

−0.043 (0.016)

0.012

 Parietal segment

Intercept

0.597 (0.013)

0.038

 < 0.001

0.507 [−0.178 to 1.188]

Group

−0.027 (0.018)

0.136

 Premotor area & SMA

Intercept

0.682 (0.015)

−0.009

 < 0.001

0.276 [−0.401 to 0.950]

Group

−0.018 (0.021)

0.412

Corticospinal tract

 Left corticospinal tract

Intercept

0.663 (0.014)

−0.030

 < 0.001

0.049 [−0.624 to 0.721]

Group

−0.003 (0.019)

0.883

 Right corticospinal tract

Intercept

0.653 (0.011)

−0.014

 < 0.001

−0.242 [−0.916 to 0.433]

Group

0.011 (0.016)

0.470

Medial lemniscus

 Left medial lemniscus

Intercept

0.621 (0.012)

0.014

 < 0.001

0.401 [−0.278 to 1.080]

Group

−0.021 (0.017)

0.234

 Right medial lemniscus

Intercept

0.639 (0.010)

0.021

 < 0.001

0.433 [−0.247 to 1.113]

Group

−0.018 (0.014)

0.199

Whole pyramidal tract

 Left pyramidal tract

Intercept

0.605 (0.011)

−0.030

 < 0.001

−0.014 [−0.687 to 0.658]

Group

0.001 (0.016)

0.965

 Right pyramidal tract

Intercept

0.614 (0.011)

−0.017

 < 0.001

−0.213 [−0.887 to 0.461]

Group

0.010 (0.015)

0.524

  1. Group = COVID-19 patients, SMA supplementary motor area, SE standard error, CI confidence interval.
  2. Significant values are in bold.