Table 4 Results of multivariate models per brain region of interest of the differences in fiber cross-section between COVID-19 patients (n = 18) and healthy controls (n = 17).
Brain region | Estimate (SE) | Adjusted R-squared | Significance level | Effect size [95% CI] (Hedges’ s g) | |
|---|---|---|---|---|---|
Corpus callosum | |||||
Motor segment | Intercept | 0.077 (0.022) | 0.050 | 0.001 | 0.552 [−0.133 to 1.237] |
Group | −0.051 (0.031) | 0.104 | |||
Parietal segment | Intercept | 0.055 (0.027) | −0.020 | 0.047 | 0.188 [−0.486 to 0.862] |
Group | −0.021 (0.037) | 0.573 | |||
Premotor area & SMA | Intercept | 0.082 (0.028) | −0.006 | 0.007 | 0.292 [−0.384 to 0.968] |
Group | −0.035 (0.039) | 0.383 | |||
Corticospinal tract* | |||||
Left corticospinal tract | Intercept | NA | NA | NA | 0.566 [−0.120 to 1.251] |
Group | 2.929+ (0.028++) | 0.096 | |||
Right corticospinal tract | Intercept | NA | NA | NA | 0.408 [−0.271 to 1.088] |
Group | 1.526+ (0.013++) | 0.225 | |||
Medial lemniscus* | |||||
Left medial lemniscus | Intercept | NA | NA | NA | 0.571 [−0.115 to 1.257] |
Group | 2.065+ (0.017++) | 0.160 | |||
Right medial lemniscus | Intercept | NA | NA | NA | 0.293 [−0.382 to 0.969] |
Group | 0.153+ (0.001++) | 0.699 | |||
Whole pyramidal tract* | |||||
Left pyramidal tract | Intercept | NA | NA | NA | 0.488 [−0.194 to 1.170] |
Group | 2.181+ (0.020++) | 0.149 | |||
Right pyramidal tract | Intercept | NA | NA | NA | 0.361 [−0.316 to 1.039] |
Group | 1.196+ (0.010++) | 0.282 | |||
