Table 6 Results of the two-group path model on the associations between cognitive performance and fiber density for COVID-19 patients (n = 18) and healthy controls (n = 17).

From: A cross-sectional case–control study on the structural connectome in recovered hospitalized COVID-19 patients

 

Healthy controls (estimate ± SE)

COVID-19 patients (estimate ± SE)

Difference (∆ estimate ± SE)

Significance level (p-value)

Regressions

 pvt ~ 

mot cc

1032.50 ± 186.17

395.92 ± 413.46

636.58 ± 453.44

0.160

par cc

−323.87 ± 77.41

−548.10 ± 159.90

224.23 ± 177.65

0.207

p&s cc

−550.50 ± 80.25

119.92 ± 264.96

−670.42 ± 276.85

0.015

pyr L

1518.89 ± 649.21

−1580.07 ± 633.36

3098.96 ± 906.98

0.001

pyr R

−719.65 ± 655.83

997.62 ± 539.19

−1717.27 ± 849.02

0.043

med L

−765.05 ± 458.75

−566.86 ± 302.53

−198.20 ± 549.52

0.718

med R

−297.98 ± 348.84

1892.19 ± 539.18

−2190.17 ± 642.18

0.001

dss ~ 

par cc

−1363.78 ± 453.38

−1135.90 ± 385.65

−227.88 ± 595.22

0.702

pyr L

3657.56 ± 2157.73

−1375.86 ± 1197.76

5033.42 ± 2467.88

0.041

pyr R

1888.98 ± 1793.90

1905.25 ± 700.83

−16.27 ± 1929.74

0.993

med L

−3907.67 ± 1736.33

−1092.41 ± 777.36

−2815.26 ± 1902.40

0.139

med R

1350.22 ± 1873.78

1959.50 ± 589.37

−609.27 ± 1964.28

0.756

mpt ~ 

mot cc

−307.89 ± 242.07

1914.10 ± 603.81

−2221.99 ± 650.53

0.001

pyr L

186.81 ± 1030.89

−5583.54 ± 1655.62

5770.35 ± 1950.34

0.003

pyr R

1475.33 ± 946.24

4322.29 ± 786.74

−2846.95 ± 1230.59

0.021

med L

−1170.62 ± 736.09

−1588.70 ± 632.79

418.08 ± 970.70

0.667

med R

73.69 ± 594.31

3799.03 ± 924.20

−3725.34 ± 1098.80

0.001

Covariances

 pvt ~~ 

dss

2474.50 ± 1088.38

−1550.362 ± 773.055

  
 

mpt

1761.63 ± 621.41

2126.565 ± 754.269

  

 dss ~~ 

mpt

4668.13 ± 1787.16

686.247 ± 1674.307

  

Intercepts

 

pvt

270.11 ± 170.10

−271.81 ± 235.53

  

dss

125.81 ± 570.48

981.75 ± 363.27

  

mpt

351.39 ± 277.59

−1437.05 ± 350.88

  

Variances

 

pvt

1301.23 ± 407.88

1723.39 ± 549.93

  

dss

11,890.18 ± 4147.64

9742.43 ± 3800.60

  

mpt

2813.03 ± 954.31

6105.12 ± 2076.29

  
  1. mpt motor praxis test, dss digit symbol substitution test, pvt psychomotor vigilance test, mot cc motor segment of the corpus callosum, par cc parietal segment of the corpus callosum, p&s cc premotor and supplementary motor segment of the corpus callosum, med L left medial lemniscus, med R right medial lemniscus, pyr L left whole pyramidal tract, pyr R right whole pyramidal tract, SE standard error.
  2. Significant values are in bold.
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