Table 3 Serum parameters and ovarian redox parameters.

From: Maternal and paternal obesity differentially reprogram the ovarian mitochondrial biogenesis of F1 female rats

 

F1-CP

F1-OF

F1-OM

F1-OP

Serum FBG (mg/dl)

89.8 ± 5.9

153.0a ± 43.4

144.5a ± 33.5

138.6a ± 19.8

Serum Insulin (µIU/ml)

9.1 ± 1.0

16.9a ± 2.2

17.6a ± 0.9

18.8a ± 2.3

HOMA-IR

2.0 ± 0.3

6.2a ± 1.3

6.2a ± 1.2

6.5a ± 1.4

Serum TG (mg/dl)

71.4 ± 8.6

118.7a ± 14.6

171.5ab ± 30.2

167.8ab ± 13.8

Serum TC (mg/dl)

106.5 ± 10.9

118.9 ± 9.8

136.9ab ± 14.2

148.8ab ± 15.9

Serum HDL-C (mg/dl)

59.3 ± 8.5

48.7a ± 3.9

62.0b ± 8.1

62.4b ± 8.2

Serum LDL-C (mg/dl)

33.0 ± 7.2

46.4 ± 8.1

40.6 ± 10.6

53.5a ± 19.4

Serum TAC (µmol/ml)

100.1 ± 5.5

86.5a ± 6.1

81.3a ± 4.7

71.1abc ± 5.3

Ovarian TAC (µmol/mg protein)

6.7 ± 1.6

3.8a ± 0.4

3.9a ± 0.5

3.2a ± 0.6

Ovarian MDA (nmol/gm tissue)

64.0 ± 10.8

80.7 ± 13.4

85.7a ± 14.9

104.5ab ± 19.8

  1. Data are presented as mean ± SD and n = 8.
  2. F1 first generation female offspring, CP control parents, OF obese father, OM obese mother, OP obese parents, FBG fasting blood glucose, HOMA-IR homeostasis model of assessment-insulin resistance index, TC total cholesterol, TG triglycerides, MDA malondialdehyde, TAC total antioxidant capacity).
  3. aSignificantly different compared with offspring of control parents, bsignificantly different compared with offspring of obese fathers, csignificantly different compared with offspring of obese mothers by ANOVA followed by Post Hoc test (Tukey), at P < 0.05.