Figure 3
Simulation of the effect of (A) single interventions, (B) pairs of boosted interventions and (C) pairs of reduced interventions. The effects are estimated as difference in resistance prevalence (%) compared to the prevalence observed before intervention, calculated assuming an increase or decrease of 10% for each parameter. The color scale (centered at 0%) goes from decreased prevalence (blue) to increased prevalence (red). KH: per-capita contact rate (daily contacts per HCW per patient); ε: treatment duration (LOS fraction); ξ: increased risk of acquiring resistance for antibiotic (AB) pressure; d: average discharge rate (inverse of LOS); pR: resistance prevalence at admission; h: hand hygiene compliance (probability of correct hand washing after contact); q: fraction of HCWs allocated to cohorting (removed from the population); ωSF: clearance rate of colonized by susceptible strains; ωRF: clearance rate of colonized by resistant strains.
