Table 2 Plasma lipid profile (mg/dl), adipocyte hormones (µg/L), nitric oxide (µmol/ml) levels and blood pressure (mmHg) of obese rats treated with zinc oxide nanoparticles.

From: Zinc nanoparticles ameliorated obesity-induced cardiovascular disease: role of metabolic syndrome and iron overload

Treatment Parameter

Control

Obese

O + ZnONPs

5 mg/kg

O + ZnONPs

10 mg/kg

Cholesterol

95.16 ± 2.95

211.5 ± 4.724*

134.1 ± 2.962*@

89.75 ± 7.034@#

Triglycerides

70.22 ± 1.78

244 ± 14.58*

204.5 ± 15.47*

173.7 ± 13.75*@

HDL

39.07 ± 2.44

7.55 ± 0.4734*

29.22 ± 2.45*@

41.6 ± 2.576@#

LDL

22.76 ± 1.36

92.51 ± 1.68*

44.94 ± 2.362*@

26.26 ± 0.9407@#

Atherogenic index

0.26 ± 0.03

1.51 ± 0.0416*

0.8492 ± 0.0583*@

0.6175 ± 0.0394*@#

Leptin

1.87 ± 0.15

3.11 ± 0.15*

2.19 ± 0.25*@

1.94 ± 0.19@#

Adiponectin

196 ± 10.31

51.13 ± 1.49*

151.88 ± 8.33*@

188.13 ± 8.80@#

Nitric oxide

40.80 ± 1.16

17.88 ± 0.78*

26.00 ± 1.05*

38.50 ± 1.68@#

Systolic BP

117.87 ± 2.13

145.76 ± 2.95*

130.38 ± 1.06*@

121.62 ± 1.89 @

Diastolic BP

81.13 ± 1.62

102.50 ± 2.60*

88.38 ± 1.44@

80.75 ± 2.23@

  1. Each value represents the mean of 8 animals ± SE. Statistical analysis was performed using one-way ANOVA followed by Tukey–Kramer multiple comparisons test (*vs control group, @vs obese group and #vs ZnONPs 5 mg/kg) at p < 0.05. O: Obese.
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