Figure 1
From: FGF-23 is a biomarker of RV dysfunction and congestion in patients with HFrEF

Olink proteomic analysis—Volcano plots showing relative abundances of plasmatic proteins. (A) A comparison between HFrEF patients and controls. NT-proBNP, BNP and FGF-23 were among the most markedly and significantly upregulated proteins in HFrEF patients while PON-3 (Serum paraoxonase/lactonase 3) was the most significantly downregulated (B) A comparison between HFrEF patients with and without RV dysfunction. FGF-23 was the most markedly upregulated in patients with HFrEF and severe RV dysfunction compared with those with HFrEF and preserved RV function.