Table 3 Comparisons of ∆ value of primary parameters before and after NPWT between DFU group and SUC group [(\(\overline{x} \pm s\)), M (P25, P75)].

From: Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue

Variable

DFU

SUC

P value

△WBC (*10^9/L)

 − 4.70 (− 9.98, − 3.05)

 − 3.59 ± 0.49

 < 0.05

△NEUT (%)

 − 7.53 ± 1.46

 − 5.30 ± 0.89

 < 0.05

△CRP (mg/L)

 − 36.60 ± 3.91

 − 13.20 ± 1.84

 < 0.05

△PCT (ng/ml)

 − 2.39 ± 0.27

 − 1.62 ± 0.30

 < 0.05

△SOD (U/mg)

11.19 ± 2.17

8.93(7.56,13.83)

 < 0.05

△GSH (μmol/g)

141.29(97.86,193.33)

117.97 ± 18.78

 < 0.05

△MDA (nmol/mg)

 − 1.02(− 1.22, − 0.96)

 − 0.96(− 1.02, − 0.89)

 < 0.05

△T-PRDX2

0.22 ± 0.03

0.20 ± 0.02

 < 0.05

  1. Data presented as mean ± standard deviation or median with interquartile range (IQR). Differences between two groups analyzed using t test or nonparametric test (Mann Whitney U).
  2. DFU diabetic foot ulcer group, SUC skin ulcer control group, WBC white blood cell, NEUT percentage of neutrophils, CRP C-reactive protein, PCT pro calcitonin, SOD superoxide dismutase, GSH glutathione, MDA malondialdehyde, T-PRDX2 peroxiredoxin-2 protein expression in wound margin tissue. △: the change value of various indexes before and after treatment.
Back to article page