Table 4 Relationship between ∆T-PRDX2 and clinical features of skin ulcers in DFU group and SUC group[(\(\overline{x} \pm s\)), M (P25, P75)].

From: Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue

 

DFU

SUC

High change group (n = 34)

Low change group (n = 22)

P value

High change group (n = 16)

Low change group (n = 12)

P value

Age (year)

59.83 ± 9.25

60.94 ± 10.77

0.211

59.23 ± 9.08

60.08 ± 10.23

0.198

Sex

  

0.890

  

0.729

 Male

22(64.7)

16(72.7)

 

11(68.8)

9(75.0)

 

 Female

12(35.3)

6(27.3)

 

5(31.2)

3(25.0)

 

Ulcer duration (week)

  

0.943

  

0.733

 ≤ 6

8(23.5)

5(22.7)

 

5(31.2)

4(33.3)

 

 6–10

16(47.1)

11(50.0)

 

7(43.8)

6(50.0)

 

 > 10

10(29.4)

6(27.3)

 

4(25.0)

2(16.7)

 

Ulcer area (cm2)

  

0.887

  

0.885

 ≤ 5

11(32.3)

7(31.8)

 

4(25.0)

3(25.0)

 

 5–10

14(41.2)

10(45.5)

 

6(37.5)

5(41.7)

 

 > 10

9(26.5)

5(22.7)

 

6(37.5)

4(33.3)

 

Wagner

  

0.725

   

 II

14(41.2)

8(36.4)

 

 

 III

20(58.8)

14(63.6)

 

 

Ulcer healing rate after 4 weeks (%)

  

0.004

  

0.031

 Healing

19(55.9)

4(18.2)

 

13(81.2)

5(41.7)

 

 Non-healing

15(44.1)

18(81.8)

 

3(18.8)

7(58.3)

 
  1. Data are presented mean ± standard deviation or numbers (%); differences between two groups analyzed using t-test or χ2 test.
  2. DFU diabetic foot ulcer group, SUC skin ulcer control group.