Table 2 Comparison of TCGA patients’ clinical characteristics in two groups.
Patient’s parameters | Total | Low (n = 70) | High (n = 71) | P* | |
|---|---|---|---|---|---|
Age, years/n(%) | 0.7565 | ||||
< 65 | 98(69.5) | 50(61.4) | 48(46.5) | ||
≥ 65 | 43(30.5) | 20(38.6) | 23(53.5) | ||
WBC, × 109/L/n(%) | 0.7275 | ||||
< 10 | 53(37.6) | 28(40) | 25(35.2) | ||
≥ 10 | 87(61.7) | 42(60) | 45(63.4) | ||
NA | 1(0.7) | – | 1(1.4) | ||
PB blasts, %/n(%) | 0.4084 | ||||
< 40 | 16(11.3) | 10(14.3) | 6(8.5) | ||
≥ 40 | 125(88.7) | 60(85.7) | 65(91.5) | ||
BM blasts, %/n(%) | 0.3281 | ||||
< 50 | 88(62.4) | 47(67.1) | 41(57.7) | ||
≥ 50 | 53(37.6) | 23(32.9) | 30(42.3) | ||
Risk/n(%) | 0.1917 | ||||
Favorable | 30(21.3) | 19(26.8) | 11(15.5) | ||
Intermediate/normal | 77(54.6) | 34(48.6) | 43(60.6) | ||
Poor | 32(22.7) | 17(24.3) | 15(21.1) | ||
NA | 2(1.4) | – | 2(2.8) | ||
FAB classifications/n(%) | 0.7437 | ||||
M0 | 14(9.9) | 8(11.4) | 6(8.5) | ||
M1 | 32(22.7) | 17(24.3) | 15(21.1) | ||
M2 | 34(24.1) | 14(20) | 20(28.2) | ||
M3 | 14(9.9) | 8(11.4) | 6(8.5) | ||
M4 | 28(19.9) | 15(21.4) | 13(18.3) | ||
M5 | 15(10.7) | 5(7.1) | 10(14) | ||
M6 | 2(1.4) | 1(1.4) | 1(1.4) | ||
M7 | 1(0.7) | 1(1.4) | – | ||
NA | 1(0.7) | 1(1.4) | – | ||
Gene mutation | |||||
FLT3 | 41(29) | 14(20) | 27(38) | 0.01851 | |
IDH1 | 26(18.4) | 18(25.7) | 8(11.3) | 0.0461 | |
NPM1c | 33(23.4) | 10(14.3) | 23(32.4) | 0.01927 | |
OS/n(%) | < 0.001 | ||||
Alive | 52(36.9) | 36(51.4) | 16(22.5) | ||
Dead | 89(63.1) | 34(48.6) | 55(77.5) | ||
