Figure 4
From: Remdesivir increases mtDNA copy number causing mild alterations to oxidative phosphorylation
Next-generation sequencing finds no change in mutational load to liver after remdesivir treatment. (a) IGV snapshot of sequencing depth and coverage maps. (b) Quantification of single nucleotide polymorphisms (SNPs) detected per 10 kilo base-pairs per sample. One dot equals an individual animal. (c) Cartoon depiction mapping polymorphisms found in NGS data on the mouse mitochondrial genome. Biorender.com was used in the generation of this panel.
