Table 2 Clinicopathological characteristics of the subject.
From: Efficacy of cell-free DNA as a diagnostic biomarker in breast cancer patients
Variables | BC patients (Mean ± SD) | Healthy control (Mean ± SD) | P value |
|---|---|---|---|
Number | 84 | 152 | Â |
Serum DNA yield (ng/µl) | 1482 ± 1.7 | 437.4 ± 4.1 |  < 0.001 |
Hb | 11.4 ± 1.4 | 21.2 ± 1.0 | 0.25 |
WBCs | 7.2 ± 2.6 | 7.4 ± 0.8 | 0.41 |
PLTs | 302.7 ± 1.3 | 295.3 ± 7.6 | 0.59 |
Urea | 26.3 ± 7.5 | 16.2 ± 4.4 |  < 0.001 |
Creatinine | 0.76 ± 0.2 | 0.69 ± 0.1 |  < 0.001 |
T. Bilirubin | 52 ± 0.2 | 0.75 ± 0.2 |  < 0.001 |
ALT | 41.5 ± 4.1 | 24.2 ± 5.9 |  < 0.001 |
AST | 40.6 ± 3.4 | 23.4 ± 0.8 |  < 0.001 |
ALP | 142.1 ± 0.8 | 111.6 ± 0.2 |  < 0.001 |
HER2 n(%) | |||
Positive | 39 (46.4) | 0 (0) |  < 0.001 |
Negative | 45 (53.6) | 152 (100) | |
ER n(%) | |||
Positive | 51 (60.7) | 0 (0) |  < 0.001 |
Negative | 33 (39.3 | 152 (100) | |
PR n(%) | |||
Positive | 45 (53.6) | 0 (0) |  < 0.001 |
Negative | 39 (46.4) | 152 (100) | |
TNBC n(%) | |||
Positive | 13 (15.5) | 0 (0) |  < 0.001 |
Negative | 71 (31.8) | 152 (100) | |
TPBC n(%) | |||
Positive | 13 (15.5) | 0 (0) |  < 0.001 |
Negative | 71 (84.5) | 152 (100) | |
