Figure 4 | Scientific Reports

Figure 4

From: Bioinformatical analysis of the key differentially expressed genes for screening potential biomarkers in Wilms tumor

Figure 4

Construction of protein–protein interaction networks of DEGs by STRING. (A) Differential gene protein interaction network. Red indicates up-regulated DEGs; Green indicates down-regulated DEGs. (B) Top 12 hub genes with a higher degree of connectivity. (C) Top module screened from the PPI network by MCODE plug-in. (D) KEGG pathway enrichment analysis of the top module. DEGs differentially expressed genes, STRING Search Tool for Retrieval of Interacting Genes, KEGG Kyoto Encyclopedia of Genes and Genomes, MCODE Molecular Complex Detection.

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