Figure 3 | Scientific Reports

Figure 3

From: Distinct patterns of copy number alterations may predict poor outcome in central nervous system germ cell tumors

Figure 3

(A) Number of altered (gain and loss) segments in copy number analyses of 81 germinoma and non-germinomatous GCT (NGGCT) cases. The number of altered copy number segments tended to be slightly higher in NGGCT cases than in germinoma cases, but the difference was not significant. (B) The number of altered copy number segments in germinoma displayed in a histogram. The distribution shows that most cases had a small number of altered segments (< 10, n = 22, stable), although a subgroup showed a high number of alterations (> 10, n = 11, unstable). (C) Germinoma cases with a more than 10 altered copy number segments showed shorter progression-free survival (PFS) than other cases.

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