Figure 1

Illustrations of follow-up CT non-enhanced lung images at four different time points. Follow-up CT images of a 66 years old man who underwent EGFR-TKIs therapy because of lung adenocarcinoma with exon 19 deletion mutation. (a) the baseline image before TKIs therapy, included in the baseline images; (b) the first follow-up image after TKIs therapy, included in FFT; (c) the last follow-up image before radiographic advance, included in EAR; (d) the radiographic advance image.