Table 1 Clinical characteristics in the training and internal test cohorts.

From: Early acquired resistance to EGFR-TKIs in lung adenocarcinomas before radiographic advanced identified by CT radiomic delta model based on two central studies

Characteristics

Training cohort

Internal test cohort

p-value

Age (year)

62.9 ± 9.5

60.3 ± 11.2

0.239*

Gender (M/F)

30/37

13/16

0.996 #

Smoking (0/1)

59/8

23/6

0.265 #

Location (1/2)

8/59

5/24

0.486#

Max Diameter

4.0 ± 1.7

3.9 ± 1.5

0.784*

Shrinkage Rate

0.327 ± 0.171

0.349 ± 0.155

0.555*

Response Days

301.1(137.0,343.0)

317.1(188.0,339.5)

0.949&

  1. #Chi-square test, *Student 's test, & Mann–Whitney test.
  2. Max Diameter is the maximum diameter in the maximum transverse section of lung adenocarcinoma. Shrinkage Rate is calculated by subtracting the maximum diameter in the baseline image from maximum diameter in the FFT then divided by the maximum diameter in the baseline image. Response Days are the days between the baseline scan and early acquire resistance scan. Location 1 and 2 denote central and peripheral types of lung cancer, respectively.