Figure 3 | Scientific Reports

Figure 3

From: The Warburg effect alters amino acid homeostasis in human retinal endothelial cells: implication for proliferative diabetic retinopathy

Figure 3

Levels of (A) Total non-essential amino acids (AAs) with aliphatic non-polar side chains, (B) Glycine, (C) Alanine, (D) Total essential AAs with aliphatic non-polar side chains, (E) Valine, (F) Leucine, and (G) Isoleucine in human retinal endothelial cells (HRECs) treated with osmotic control (Mannitol; 25 mM) or high glucose (HG; 25 mM) for 5 days; followed by normoxia or hypoxia (Hyp; 2% O2 and 5% CO2) for 24 h. Data are mean ± SD; n = 3–4/group; ns: no significance; **: P < 0.01; and ***: P < 0.001. Comparisons between groups were made by ANOVA followed by Sidak's post-test.

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