Figure 1
From: Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer
Increased expression of proteasome subunit genes is associated with a worse breast cancer prognosis. High expression of the 26S proteasome gene signature in primary tumor tissue is associated with decreased (A) recurrence free survival (n = 882), (B) overall survival (n = 313), and (C) distant metastasis free survival (n = 332) in patients with breast cancer. Data and graphs were generated by the breast cancer mRNA gene chip dataset in the KM Plotter database using median gene signature expression to divide patient samples into high and low expression.
