Table 3 Safety analysis in the combined with anti-angiogenosis group.
AEs | Grade 1–2 | Grade 3–4 |
|---|---|---|
Leukopenia | 23 (24.0) | – |
Thrombocytopenia | 37 (38.5) | 5 (5.2) |
Nausea and vomiting | 6 (6.2) | – |
Diarrhea or constipation | 11 (11.5) | 2 (2.1) |
Fatigue | 44 (45.8) | – |
Hypertension | 13 (13.5) | – |
Bleeding | 9 (9.4) | – |
Rash | 8 (8.3) | 1(1.0) |
Hand-foot syndrome | 12 (12.5) | – |
Pneumonia | 7 (7.3) | 1 (1.0) |