Figure 2 | Scientific Reports

Figure 2

From: Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats

Figure 2

miRNA screening. Volcano plots presenting altered miRNA expression profiles of the different conditions. In the comparison of (A) aortic-banded (AB) groups without systolic heart failure (ABLVH) versus sham group, (B) AB groups with systolic heart failure (ABHF) versus sham group and (C) ABHF group versus ABLVH group 14, 153 and 50 miRNAs showed significant differential expression, respectively. Up- (red) and downregulated (blue) miRNAs that meet the specified significance threshold conditions (P-value < 0.05 and fold change > 1.5 or < 1/1.5) are listed (for the complete list of upregulated miRNAs in ABHF group versus sham group see the Supplementary files).

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