Table 1 Patient characteristics at baseline.
Items | All subjects (N = 2247) | Stratified by the use of phosphate binders at baseline | ||
|---|---|---|---|---|
Iron-based (N = 328) | Only non-iron-based (N = 1360) | None (N = 559) | ||
Age | 66 (12) | 64 (12) | 65 (12) | 70 (12.0) |
Male sex | 68% | 67% | 67% | 70% |
Hemodialysis vintage | 3.8 [0.9,9.6] | 3.5 [0.6,7.7] | 5.1 [1.8,11.7] | 1.9 [0.3,6.3] |
Comorbidities | ||||
Diabetes mellitus | 44% | 46% | 41% | 50% |
Cardiovascular disease | 59% | 58% | 58% | 62% |
Laboratory | ||||
Hemoglobin (g/dL) | 10.9 (1.2) | 11.2 (1.3) | 11.0 (1.2) | 10.7 (1.3) |
Albumin (g/dL) | 3.6 (0.4) | 3.6 (0.4) | 3.6 (0.4) | 3.5 (0.5) |
C-reactive protein (mg/dL) | 0.1 [0.1–0.4] | 0.1 [0.1–0,3] | 0.1 [0.1–0.4] | 0.2 [0.1–0.6] |
Potassium (mEq/L) | 4.7 (0.7) | 4.8 (0.7) | 4.8 (0.7) | 4.5 (0.7) |
Calcium (mg/dL) | 8.7 (0.7) | 8.8 (0.8) | 8.8 (0.7) | 8.6 (0.7) |
Phosphate (mg/dL) | 5.3 (1.4) | 5.6 (1.5) | 5.3 (1.4) | 4.9 (1.3) |
iPTH (pg/ml) | 132 [74–225] | 140 [73–236] | 126 [72–222] | 138 [82–225] |
Transferrin saturation (%) | 23 [16–31] | 26 [18–36] | 23 [16–31] | 21 [15–30] |
Ferritin (ng/ml) | 73 [35–141] | 92 [42–171] | 67 [31–133] | 77 [36–148] |
Living alone | 15% | 12% | 16% | 14% |
ADL independence | 88% | 90% | 90% | 81% |
Medication | ||||
RAASi | 50% | 59% | 50% | 45% |
Beta-blockers | 11% | 9% | 11% | 11% |
ESA | 88% | 87% | 88% | 86% |
Iron | 38% | 24% | 42% | 37% |
Vitamin D analogs | 70% | 74% | 74% | 57% |
Calcimimetics | 22% | 24% | 27% | 8% |
