Table 6 Proteins which are increased in abundance in E. faecalis when grown in the presence of gliotoxin (5 µg/ml), compared to identical cultures grown without gliotoxin (5 µg/ml). Grown using tryptic soy broth (TSB) media for 60 min in the log phase (0.3–0.4 OD600).

From: Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion

Protein description

Fold Change (log2)

p-value

Peptides

Sequence coverage [%]

Protein IDs

Adhesion lipoprotein (adcA-II)

8.49828

0.0020639

17

47.2

Q82Z67

Adhesion lipoprotein (adcABC)

2.61741

0.00538351

8

44.8

Q839U5

Peptide ABC transporter, ATP-binding protein

1.28554

0.00946214

12

70.7

Q82ZF0

5'-nucleotidase family protein

0.948218

0.011422

23

26.9

Q839U0

LemA family protein

0.664767

0.00432472

6

40.7

Q838I0

Phage portal protein

0.64703

0.0486542

16

56

Q835K9

ABC transporter, ATP-binding protein

0.643841

0.0456337

4

35.8

Q833S0

Xanthine phosphoribosyltransferase

0.614899

0.00209845

12

84.5

Q831Y0

Adenine phosphoribosyltransferase

0.575857

0.0317383

10

71.2

Q834G6

Peptide methionine sulfoxide reductase MsrB*

1.6171

N/A

5

51.7

P0DM32

  1. *This protein was found in 2/3 GT treated samples and 1/3 untreated controls which prevented calculation of a P-value.