Table 3 Monte Carlo simulation for IRBR of placebo, 9H, 4R, 3HR and 3HP compared with 6H.
Regimen | Incremental risk (adverse events) | Incremental benefit (TB prevention) | IRBR |
|---|---|---|---|
6H | Reference | Reference | Reference |
Placebo | − 0.00001 | − 0.01296 | 0.0006 |
9H | − 0.03795 | 0.00384 | − 9.8737 |
4R | − 0.04318 | 0.00595 | − 7.2616 |
3HR | − 0.00057 | 0.00711 | − 0.0807 |
3HP | − 0.04517 | 0.00454 | − 9.9388 |