Figure 3

Community shuffling plot of the changes in bacterial network structures of SRS-positive compared to healthy Atlantic salmon. This plot illustrates the relationships between members of the bacterial families found in the fish. This graphic consists of nodes arranged in a circle. Each node represents a member of the bacterial network. The co-occurrence between bacterial network members of the infected fish are indicated by a line connecting the two specific nodes. This line is called an ‘edge’ and red, green and blue indicate associations enriched in the SRS-positive, healthy and shared bacterial networks, respectively. This graphical output highlights the sub-networks and ‘driver’ nodes. All nodes belonging to the same community are randomly assigned a similar color. Grayed-out nodes represent the ones present in both but directly interacting with the common sub-network in either infected or healthy conditions. Node sizes are proportional to their scaled NESH score, as calculated using NetShift tool. A node is colored red if its proximity increases from healthy to infected samples. Nodes that are big and red indicate that these organisms are significant ‘drivers’ in the shift from healthy to a SRS-diseased state in the localized bacterial communities.