Figure 6 | Scientific Reports

Figure 6

From: Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma

Figure 6

Differential gene expression EA and control horses. (a) Volcano plots showing DE genes from pseudo-bulk (DESeq2) analysis of alveolar macrophages (AMs), T cells, and mast cells. The plots show the results from testing the mastocytic group of horses vs controls. (b) FKBP5 and CCL24 expression levels in EA and control cells visualized on the UMAP plot. (c) Violin plots showing expression levels of FKBP5 in mast cells and CCL24 in alveolar macrophages for individual horses. IDs of healthy horses are denoted in blue and asthma horses denoted in green. (IDs of the horses that did not meet the inclusion critera are marked in red).

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