Figure 4

Construction of WGCNA modules. (a) Clustering dendrogram and trait heatmap of samples (Red indicates the RA group and white indicates the Normal group. (b) The soft thresholding and correlation coefficient in the scale-free topology fitting graph. (c) Histogram of the connectivity distribution and the scale-free topology. (d) The dendrogram of differentially expressed genes (Clustering based on dissimilarity measures). (e) Module and trait-related heat map. (f) A scatterplot of Gene Significance (GS) for weight versus Module Membership (MM) in the module darkorange2. There is a highly significant correlation between GS and MM in this module.