Figure 4
The effects of environmental enrichment on social behavior. (a) Image of the three-chamber social paradigm. (b) Standard housing BTBR mice spent a similar amount of time in the social and object chambers and less time in the middle chamber (One-way ANOVA: F(2, 54) = 14.89, p < 0.0001). (c) BTBR mice in the enriched condition spent more time in the social chamber than the object chamber and spent the least time in the center (One-way ANOVA: F(2, 57) = 27.80, p < 0.0001). (d, e) B6 mice in both the standard (d) and enriched (e) conditions spent more time in the social chamber than the object chamber and spent the least time in the center (One-way ANOVA: (d) F(2, 51) = 40.53, p < 0.0001 and (e) F(2, 51) = 40.43, p < 0.0001). For every graph, the listed p values were obtained with Tukey post-hoc tests -comparison values between the social and object chambers are depicted. ns: not significant.
