Table 2 Multiple linear regression analysis of SVHD cases versus controls.

From: Circulating biomarkers of extracellular matrix dysregulation are associated with adverse post-stage 2 outcomes in infants with single ventricle heart disease

Protein

Coefficient

p-valuE

FGF 23

1.30E+00

8.60E-09

MMP 13

1.02E+00

8.04E-08

MMP 16

9.41E-01

9.43E-08

FGF 20

8.64E-01

7.65E-07

TIMP 2

1.08E + 00

1.52E-06

FGF 4

7.37E-01

2.37E-05

MMP 2

9.45E-01

3.76E-05

FGFBP1

8.07E-01

3.97E-05

FGF 5

0.810707

0.000147

MMP 17

0.589192

0.001133

MMP 7

0.833692

0.001717

FGF 12

0.714738

0.00247

FGF 18

0.491514

0.00397

FGF 3

0.570472

0.005341

FGF 6

0.628252

0.005475

MMP 20

− 0.48239

0.017481

FGF 9

0.562842

0.018628

TIMP 1

0.58405

0.024967

FGFR1

0.548051

0.03642

MMP 8

0.540144

0.040557

  1. Proteins whose circulating abundance differs between cases and controls after adjusting for sex and heparin status. Positive coefficients indicate higher abundance in SVHD cases than controls whereas negative coefficients indicate higher protein abundance in controls. SVHD = single ventricle heart disease, MMP = matrix metalloprotease, FGF = fibroblast growth factor, TIMP = tissue inhibitor of metalloprotease.
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