Figure 8 | Scientific Reports

Figure 8

From: Chronic dehydration induces injury pathways in rats, but does not mimic histopathology of chronic interstitial nephritis in agricultural communities

Figure 8

IPA-based disease & bio-function pathway enrichment analysis of cyclosporine or dehydration DEP lists. Cyclosporine administration in rats upregulates proteins (red) involved in processes linked to cellular pathology and oxidative stress, while downregulating proteins involved linked with fatty acid metabolism and glucometabolic dysfunction. Dehydration cohort proteins (blue) depict a minimal degree of classical disease/bio-function annotation, suggesting a less coherent molecular signalling response.

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