Figure 2

Complexity and diversity features of HBV quasispecies. (A) Shannon entropy (outer circle) and mutation frequencies (inner circle) observed in HBV polymerase (RT domain; green) and HBsAg (blue). The frequency of substitutions in both genes is expressed by the scale bar. The (B) chord diagram demonstrates the connections between molecular features and HBV functional domains. The proportions of each feature are indicated by the lengths of the Arc.